Practical training is an important aspect of experimental pharmacology. This book is collection of specific methods used in understanding of basic principles of experimental pharmacology. In this an attempt has been made to highlight the practical areas of experimental pharmacology with intention to help students to learn basics in experimental pharmacology, various screening methods, their models and concept that provide advanced understanding of the subject. It provides a concise account of the Preliminary methods and General Principles which form the basis of pharmacological experimentation. We tried to achieve maximum coverage in the simplest way.