Rapid Development in Computer technology have made individuals to become computer literate. The main objective of this book is to explain about concept of computer, health informatics and their applications in various fields to a beginner. This book has been structured to help the students of Nursing.This book explains in brief the role of computers for nursing and principles of health informatics which is the basis for conducting any Hospital or Nursing establishments. Content of this book is explained in Ten Units. The first Unit deals about the concepts of computer, Windows, MS Office, Word, Excel, Power Point, Internet, Literature Search, Hospital Management information system. Second unit deals about Principles of Health Informatics. Third Unit contains Information Systems in Health Care. Forth Unit contains Electronic Health Records. Fifth Unit deals about Patient Safety and Clinical Risk. Sixth Unit deals about Clinical Knowledge and Decision Making. Seventh Unit contains eHealth:Patients and the Internet. Eighth Unit contains Using Information in Healthcare Management. Ninth Unit deal about Information Law and Governance in Clinical Practice.Finally the tenth unit is about Healthcare Quality and Evidence Based Practic.