The new addition presents the fundamentals of all the four major spectroscopic methods: nuclear magnetic resonance spectroscopy, vibrational spectroscopy, electronic spectroscopy and mass spectrometry which includes modern ionization techniques (electrospray, MALDI and others), which have greatly enhanced applications of MS to large molecules. The most up-to-date treatment of NMR, including (2D) NMR as a new chapter; Thorough and current treatment of mass spectrometry which includes ionization methods; Includes coverage of circular dichroism and optical rotatory dispersion; a variety of problems in each chapter and integrated exercises in Chapter 8.