The purpose of this book is to provide essential knowledge of clinical biochemistry in an easily assimilable form. While it is aimed at the students of medicine at the preclinical phase where biochemistry forms one of the major subjects it would also be equally helpful to postqraduate science students in biochemistry.The emphasis in the book has been given not only on the principles and methodology of the biochemical parameters but also on clinical interpretations and role in health/disease. One of the major features of this book is the inclusion of problems/case-based biochemical discussions in relevant chapters. The book covers all aspects of practical biochemistry including qualitative and quantitative estimations of biochemical parameters analytes and enzymes vis- -vis organ functions. Furthermore the chapters on molecular biology DNA-based diagnostic techniques along with radioimmunoassay and ELISA have been incorporated which would update the readers to the present-day advances.