Spectacular advances in modern science and technology have made our lives more comfortable but not necessarily healthier or more peaceful. We are facing serious existential risks for nature and humanity where the developments are challenging our understanding. Genome to Om explores the desired transition from modern science to meta-science, blending ethical, moral, and spiritual insights while recognizing the interconnectedness of all aspects of life. It emphasizes a holistic scientific approach, talking of the marvels of science and technology, and the consequent perils that have engulfed all living beings and the planet itself. The authors pose intriguing questions about the wonders of the cosmos, life?s origin, and most of all, the goal and purpose of life?s journey. Genome represents the dynamic modern science, while Om embodies universal consciousness as the ultimate reality. This book is an endeavour to bridge the gap between empirical knowledge and higher-order wisdom, advocating an innovative, inclusive, technologically advanced, yet spiritually enriched and ethically grounded future. The daring proposal seeks the possibility of progressing from the Anthropocene to an ideal Omcene epoch. Genome to Om offers hope for the meaningful progression to a meta-society, and the onward journey towards harmony between scientific progress and timeless human values to reach our full potential seeking unity in diversity for universal peace and well-being, and to continue the journey of life, the Om Way.