The special characteristic of this book is that Dr. Hughes, himself a great physician, has thoroughly availed himself of the experiences of his predecessors and colleagues all over the world, enriched by his own, and has never been wanting in recommending the findings of others, whenever necessary. The essential character of Hughes' homeopathy was that it stood at the scientific end of the homeopathic spectrum of opinion. He put the similia principle at the center of the scene. Hughes believed that if you are serious about the idea of similia, you should consider the pathology. Drugs should be chosen not only based on the subjective symptoms they produce but also based on their known pathological effects in humans and even animals.