Harrison?s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world?s top experts are featured in the 21st edition: ? Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer ? Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries ? More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes ? Numerous atlases featuring curated collections of important visual aspects of diagnosis and management ? Updated and time-saving curation and synthesis of established and new medical literature and studies ? Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms