This book based on Manipal Medical Manual which has been an immensely popular handbook for more than two decades among the students and residents in the department of medicine of every institution. This Manual, known for its concise presentation of the recognition and management of medical emergencies and infections, required a thorough revision to keep up with the expanding medical knowledge, changing evidence, and technological advancements. In this edition, retitled Manipal Manual of Emergency Medicine and Critical Care, several chapters have been rewritten and many new ones added. The book retains its clarity and ease of reference due to its simple point-wise description format. The authors have made all attempts to incorporate the best practices in the management of medical illnesses, basing the chapters on standard guidelines. The Manual will continue to hold its unique position among medical books as a concise and dependable source of information.